There’s a world below clouds and enterprise environments with thousands of VMs and hundered or thousands of hosts. A world that consists of maximal three hosts. I’m working with quite a few customers, that are using VMware vSphere Essentials Plus. Those environments consist typically of two or three hosts and something between 10 and 100 VMs. Just to mention it: I don’t have any VMware vSphere Essentials customer. I can’t see any benefit for buying these license.
Nutanix was founded in 2009 and left the stealth mode in 2011. Their Virtual Computing Platform combines storage and computing resources in a building block scheme. Each appliance consists up to four nodes and local storage (SSD and rotating rust). At least three nodes are necessary to form a cluster. If you need more storage or compute resources, you can add more appliances, and thus nodes, to the cluster (scale out).